Press Releases
January 03, 2017
Kite Pharma Submits Investigational New Drug (IND) Application for KITE-718, an Investigational Next Generation T-Cell Receptor (TCR) Therapy Targeting Cancer Antigens MAGE A3 and MAGE A6
- Directed Against a Validated TCR Target in Solid Tumors
- Built on the National Cancer Institute Proof of Concept Work and Optimized to Include Next Generation T-cell Manufacturing Technologies
"Submission of this IND is an important milestone for our solid tumor strategy utilizing engineered T cell therapy based on both TCR and CAR platform technology," said
KITE-718 is built on the proof of concept data established by the National Cancer Institute's (NCI) MAGE A3/A6 TCR program (NCT02111850). No off-target toxicity was observed in the NCI study, and evidence of tumor regression was seen in patients with multiple types of solid tumors. KITE-718 has been optimized from the foundational work at the NCI by streamlining the manufacturing process through advanced technologies and next-generation cell manufacturing conditions.
About
Cautionary Note on Forward-Looking Statements
This press release contains forward-looking statements for purposes of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The press release may, in some cases, use terms such as "predicts," "believes," "potential," "proposed," "continue," "estimates," "anticipates," "expects," "plans," "intends," "may," "could," "might," "will," "should" or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. Forward-looking statements include statements regarding intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things: the ability to advance and the success of KITE-718 directed against MAGE A3/A6 antigens. Various factors may cause differences between Kite's expectations and actual results as discussed in greater detail in Kite's filings with the
View source version on businesswire.com: http://www.businesswire.com/news/home/20170103005437/en/
SVP, Corporate Communications & Investor Relations
ccassiano@kitepharma.com
or
VP, Investor Relations
gmann@kitepharma.com
Source:
News Provided by Acquire Media