External-Sponsored Research
We are committed to generating and supporting critical, high-quality research that has an impact on clinical decision-making and patients’ lives. Our External-Sponsored Research Program provides funding and/or study drug support for research efforts conducted by third parties on Gilead products or therapeutic areas. For research on cell therapy, please visit Kite Cell Therapy External Research Program.
We support two primary types of research, Investigator-Sponsored Research and Collaborative Research. We also support research where the study sponsor is a government organization, nonprofit organization or a pharmaceutical company.
In addition, we support research focused on and led by community organizations. Information is available on the Community-Based Participatory Research page.
Types of External-Sponsored Research
Investigator-Sponsored Research (ISR) is initiated, designed, and led by independent researchers. For an ISR project, an investigator or institution outside of Gilead is the study sponsor. If the research concerns a Gilead product, the study must occur after regulatory approval of the product in the country where the study will be conducted. Gilead’s only involvement in an ISR project is solely funding and/or study drug support. We request to check the study protocol to confirm the study design and safety reporting requirements. We also request a courtesy review of all abstracts and publications.
Collaborative Research is similar to ISR where the study sponsor is an investigator or institution outside of Gilead. However, Gilead is typically involved in Collaborative Research beyond providing funding and/or study drug, such as developing the study design, protocol development/review, conduct of study, providing data/biological samples, data/sample analysis, and publication preparation/authorship. Abstracts and publications may be co-authored with Gilead.
RFP Opportunities
A Request for Proposal (RFP) aims to address unmet patient needs in specific populations such as through innovative methods for screening, diagnosis, and care access initiatives, while also garnering insights on disease epidemiology and treatment.
There are two types of RFP:
-
RFP Program is a call for research on a specific topic and question of interest described in detail, usually with additional instructions regarding the application process. They are highly competitive and typically have a submission window of only a few weeks.
-
RFP Topic of Interest is a brief posting of a specific area of research need without great detail about the topic or additional instructions regarding the application process. They may have a longer submission window or remain posted until funds are exhausted.
If you're interested in applying to an RFP Program, review the research question ask and follow the instructions within the program descriptions about submitting a Letter of Interest and about next steps if invited to submit a full proposal. For any queries, contact the email listed in the RFP Program description or your local Gilead contact.
If you apply for an RFP Topic of Interest, review the research topics below and indicate the topic you are applying for in your Letter of Interest submission. Submit a full proposal after you receive an invitation. For queries on the listed topics, contact your local Gilead contact.
RFP Programs
HIV Treatment: RESONATE 2024 RFP Program (Deadline Oct 14, Nov 18)
RESONATE supports the development of additional scientific data to improve clinical and community decisions and medical management of HIV.
Hepatitis D: SPEARHEAD 2024 RFP Program (Deadline Sep 27)
SPEARHEAD was relaunched in 2024 and is open to global submissions. It aims to enhance understanding and address challenges related to HDV screening and linkage to care.
Hepatitis D: DETER 2024 RFP Program (Deadline Sep 27)
There remains a need for robust real-world data to inform and guide clinical practice for the treatment of HDV. The aim of this program is to generate real-world treatment data to supplement findings from clinical trials.
Primary Biliary Cholangitis: HANDLE RFP Program (Deadline Sep 1)
This program was launched to characterize and address the unmet medical needs in PBC. Research topics of interest include elucidating the natural history and outcomes of PBC, optimizing the care cascade, validating non-invasive tests and characterizing and addressing the symptom burden.
RFP Topics of Interest
To be announced in Fall 2024.
How to Apply for Research Funding
To submit an application for any External-Sponsored Research funding or other study support, visit Gilead’s online proposal submission portal, Gilead OPTICS (G.OPTICS). If you are applying to an RFP Program or RFP Topic of Interest, start with a Letter of Interest submission. Submit a full proposal once you receive an invitation.
Collaborative Research should also start with a Letter of Interest — which can be related to an RFP or independent of an RFP — unless you have been invited by Gilead to submit a full proposal. Research with study sponsor that is a government or nonprofit organization or other pharmaceutical company should also start with a Letter of Interest unless invited to submit a full proposal.
How To Register In Gilead OPTICS
We support External-Sponsored Research contingent on the proposal's scientific merit. The research must be intended to contribute knowledge to the medical community and the budget must be reasonable and appropriate for the proposed work. We evaluate applications considering the expertise of the principal investigator and any sub-investigators, including their proficiency in the relevant therapeutic field, track record in conducting successful clinical trials, and available resources.
Our cross-functional committees review all External-Sponsored Research proposals. If either an ISR or Collaborative Research study is awarded support, the principal investigator, as the study sponsor, will have full discretion and responsibility for all aspects of study design, implementation, analysis, data dissemination and compliance with relevant laws. The terms of Gilead's support will be outlined in a written agreement; funding is not guaranteed for your proposal as funding will be provided specifically to support research activities.
Some of the content on this page is not intended for users outside the United States.