April 25, 2006

Gilead Closes Sale of $1.3 Billion Convertible Senior Notes

FOSTER CITY, Calif.--(BUSINESS WIRE)--April 25, 2006--Gilead Sciences, Inc. (Nasdaq:GILD) today announced the closing of its sale of $650 million principal amount of Convertible Senior Notes due 2011 and $650 million principal amount of Convertible Senior Notes due 2013 to qualified institutional buyers pursuant to Rule 144A under the Securities Act of 1933, as amended (the "Securities Act"). The aggregate principal amount of Convertible Senior Notes sold reflects the full exercise by the initial purchasers of their option to purchase additional Convertible Senior Notes to cover over-allotments. The net proceeds from this offering were approximately $1.28 billion, after deducting estimated discounts, commissions and expenses.

This notice does not constitute an offer to sell or a solicitation of an offer to buy securities. Any offers of the securities will be made only by means of a private offering memorandum. The securities offered have not been registered under the Securities Act or the securities laws of any other jurisdiction and may not be offered or sold in the United States absent registration or an applicable exemption from registration requirements.

About Gilead Sciences

Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. Headquartered in Foster City, California, Gilead has operations in North America, Europe and Australia.

Forward-Looking Statement

Forward-looking statements, including the statements in this notice regarding Gilead's estimate of the expenses payable by it in connection with the transactions described in this release, and therefore the net proceeds of such transactions, are subject to risks and uncertainties.

CONTACT: Gilead Sciences, Inc. Susan Hubbard, 650-522-5715 (Investors) Amy Flood, 650-522-5643 (Media) http://www.gilead.com SOURCE: Gilead Sciences, Inc.

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