Gilead Sciences' Chairman and Chief Executive Officer Establishes Rule 10b5-1 Stock Trading Plan

FOSTER CITY, Calif.--(BUSINESS WIRE)--May 22, 2008--Gilead Sciences, Inc. (Nasdaq:GILD) today announced the establishment of a new stock trading plan under Rule 10b5-1 of the Securities Exchange Act of 1934 on May 22, 2008 by John C. Martin, PhD, Chairman and Chief Executive Officer of Gilead. Commencing in September 2008, Dr. Martin's plan provides for the exercise and sale of certain options each month on pre-determined dates through July 2010.

The transactions under the plan are disclosed publicly through Form 144 and Form 4 filings with the Securities and Exchange Commission. James M. Denny, Gilead's lead independent director of the Board, Paul Berg, PhD, a member of Gilead's Board of Directors, John F. Milligan, PhD, President and Chief Operating Officer, Kevin Young, Executive Vice President, Commercial Operations, Gregg H. Alton, Senior Vice President and General Counsel, and Kristen M. Metza, Senior Vice President, Human Resources, maintain stock trading plans under Rule 10b5-1, and other officers and directors of the company may do so in the future.

Rule 10b5-1 allows insiders to adopt written plans for trading securities in a non-discretionary, pre-scheduled manner in order to avoid concerns about initiating stock transactions when the insider may be aware of non-public information. Such plans also allow insiders to diversify their holdings and to minimize the market effect of stock sales by spreading them out over time.

About Gilead

Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide. Headquartered in Foster City, California, Gilead has operations in North America, Europe and Australia.

For more information on Gilead Sciences, please visit www.gilead.com or call the Gilead Public Affairs Department at 1-800-GILEAD-5 (1-800-445-3235).

CONTACT: Gilead Sciences, Inc. Susan Hubbard, 650-522-5715 (Investors) Amy Flood, 650-522-5643 (Media) SOURCE: Gilead Sciences, Inc.