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- Clinical and Biomarker Correlates of Outcomes in ZUMA-1 Pivotal Trial of axicabtagene ciloleucel in Refractory, Aggressive Non-Hodgkin Lymphoma (NHL)
- Updated Efficacy and Safety Data from ZUMA-3, a Phase 1/2 study of KTE-C19 in Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)
- Health Economics and Outcomes Research Abstract on Current Treatment Cost for Diffuse Large B-Cell Lymphoma (DLBCL)
"The presentations at ASCO continue to enhance our growing knowledge on the potential for cell therapy," said
Poster Discussion:
Clinical and biologic covariates of outcomes in ZUMA-1: a pivotal trial of axicabtagene ciloleucel (axi-cel; KTE-C19) in patients with refractory aggressive non-Hodgkin lymphoma (r-NHL)
- Abstract #7512
- Session: Poster Session: Hematologic Malignancies - Lymphoma and Chronic Lymphocytic Leukemia
- Poster Board #274
- Session Time/Location:
Monday, June 5, 2017 :8:00-11:30 AM CDT , Hall A - Poster Discussion Session Time/Location:
Monday, June 5, 2017 :1:15-2:30 PM CDT , E354b - Presenter:
Frederick L. Locke , M.D.,Moffitt Cancer Center ,Tampa, FL
Poster Presentations
Updated results from ZUMA-3, a phase 1/2 study of KTE-C19 chimeric antigen receptor (CAR) T cell therapy, in adults with high-burden relapsed/refractory acute lymphoblastic leukemia (R/R ALL)
- Abstract #3024
- Session: Poster Session: Developmental Therapeutics - Immunotherapy
- Poster Board #119
- Session Time/Location:
Monday, June 5, 2017 :8:00-11:30 AM CDT , Hall A - Presenter:
Bijal D. Shah , M.D.,Moffitt Cancer Center ,Tampa, FL
Product characteristics associated with in vivo expansion of anti-CD19 CAR T cells in patients treated with axicabtagene ciloleucel (axi-cel)
- Abstract #3023
- Session: Poster Session: Developmental Therapeutics - Immunotherapy
- Poster Board #118
- Session Time/Location:
Monday, June 5, 2017 :8:00-11:30 AM CDT , Hall A - Presenter:
Frederick L. Locke , M.D.,Moffitt Cancer Center ,Tampa, FL
Characterization of anti-CD19 chimeric antigen receptor (CAR) T cell-mediated tumor microenvironment immune gene profile in a multicenter trial (ZUMA-1) with axicabtagene ciloleucel (axi-cel, KTE-C19)
- Abstract #3025
- Session: Poster Session: Developmental Therapeutics - Immunotherapy
- Poster Board #120
- Session Time/Location:
Monday, June 5, 2017 :8:00-11:30 AM CDT , Hall A - Presenter:
Jerome Galon , Ph.D.,Laboratory of Integrative Cancer Immunology ,INSERM
ZUMA-6:Phase 1-2 multicenter study evaluating safety and efficacy of axicabtagene ciloleucel (axi-cel; KTE-C19) in combination with atezolizumab in patients with refractory diffuse large B-cell lymphoma (DLBCL)
- Abstract #TPS7572
- Session: Trials in Progress Poster Session: Hematologic Malignancies - Lymphoma and Chronic Lymphocytic Leukemia
- Poster Board #331a
- Session Time/Location:
Monday, June 5, 2017 :8:00-11:30 AM CDT , Hall A - Presenter:
Frederick L. Locke , M.D.,Moffitt Cancer Center ,Tampa, FL
Online Publication
Total 1-year cost of diffuse large B-cell lymphoma (DLBCL) beyond first-line (1L) therapy:A retrospective cohort analysis
- Abstract # e18333
- Senior Author:
Anna Purdum , PharmD, M.S.,Kite Pharma
About axicabtagene ciloleucel
Kite's lead product candidate, axicabtagene ciloleucel, previously known as KTE-C19, is an investigational therapy in which a patient's T cells are engineered to express a chimeric antigen receptor (CAR) to target the antigen CD19, a protein expressed on the cell surface of B-cell lymphomas and leukemias, and redirect the T cells to kill cancer cells. Axicabtagene ciloleucel has been granted Breakthrough Therapy Designation status for diffuse large B-cell lymphoma (DLBCL), transformed follicular lymphoma (TFL), and primary mediastinal B-cell lymphoma (PMBCL) by the U.S. Food and Drug Administration (FDA) and Priority Medicines (PRIME) regulatory support for DLBCL in the EU.
About Kite
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.
Cautionary Note on Forward-Looking Statements
This press release contains forward-looking statements for purposes of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The press release may, in some cases, use terms such as "predicts," "believes," "potential," "proposed," "continue," "estimates," "anticipates," "expects," "plans," "intends," "may," "could," "might," "will," "should" or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. Forward-looking statements include statements regarding intentions, beliefs, projections, outlook, analyses or current expectations concerning, among other things: the ability to advance axicabtagene ciloleucel/KTE-C19 and optimize treatment in NHL and across a broad range of hematologic malignancies. Various factors may cause differences between Kite's expectations and actual results as discussed in greater detail in Kite's filings with the
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